- The vaccine would be effective for between six months and a year
- It sends a message to the liver not to express genes that metabolize alcohol
- Trials on mice begin next month with human tests planned for November
A new vaccine will give anyone who drinks even a small amount of alcohol an immediate and very heavy hangover.
Scientists from the University of Chile have spent a year designing the drug in a bid to tackle the growing problem of alcoholism in the country.
The vaccine, which would be effective for between six months and a year, works by sending a biochemical message to the liver telling it not to express genes that metabolise alcohol.
Normally, the liver turns alcohol into the hangover-causing compound called acetaldehyde which is then broken down by a metabolising enzyme.
If someone who’s been vaccinated tries to drink alcohol, they will immediately experience severe nausea, accelerated heartbeat, and general discomfort.

